Vivien‘s first first-author paper entitled “Effects of Abnormal Muscle Forces on Prenatal Joint Morphogenesis in Mice” has been published in the Journal of Orthopaedic Research. The paper characterises the effects of absent or reduced muscle on prenatal development of the major synovial joints. Vivien used image registration to qualitatively and quantitatively compare joint shapes between muscleless, reduced-muscle and normal mice. Different joints were affected more than others, and what we found most interesting is that a reduction in muscle often led to *more* severe effects than no muscle- like in the humeral distal condyles (blue: control, yellow: reduced-muscle, purple: muscleless)
Congratulations Vivien! You can access the final version of the paper here, or the submitted version here if you don’t have access to JOR.
Developmental Biomechanics 